Axert is the trade name of a prescription drug containing almotriptan as the active component.
Almotriptan is a found in a class of drugs called triptans and is used in the treatment of acute (intense) migraines attacks without or with aura, it is not use as a prophylactic treatment for migraines. Axert is manufactured by Janssen Pharmaceuticals, the drug is available in pack size of 6 tablets. The tablets are whitish, circular, biconvex and coated tablets with the figure “2080” imprinted in red.
Axert works by attaching itself to certain areas in the brain regulates its actions and thus leading to vasoconstriction of the blood vessels in the brain, then causing a reduction in the flow of blood in the cranial vessels thereby helping to stop migraines.
Almotriptan like most triptans has specific affinity for serotonin receptors (chemical in the brain), almotriptan causes vasoconstriction of blood vessels (cranial) in the brain and thus impacts on the redistribution of blood flow, leading to reduced blood flow in extra cerebral and increased cerebral blood flow in cranial vessels. A single dose of almotriptan has a huge effect on the cranial blood vessels but it has no effect on heart rate, or blood pressure in elderly and young people, however larger doses do have an effect.
There are no approved generic brands of almotriptan approved by the FDA for use in USA.
The recommended dose of Axert is 6.25 mg to 12.5 mg, the choice of dose should be made on an individual basis, because people tend to vary in their response to the doses consumed.
A dose can be repeated after two hours if the headache returns.
The max daily dose should not exceed 25 mg and almotriptan should not be used to treat more than four migraine attacks within 30 days.
Axert like all other drugs may exhibit some side effects, these side effects may range from mild (normally disappear) to severe (stop its use when the severe cases appear). Below is a list of some side affects you may experience with Axert use.
Note: This list may not be complete therefore you should report any new experience or feeling occurring after the use of Axert.
Taking Axert with certain drugs can either potentiate their effects in the body or nullify them, it may affect the manner in which these drugs work or vice versa. Therefore you should know the medicines you take and always remember to tell your healthcare provider and pharmacist when you are prescribed new medicine. Below are examples of medicines that may interact Axert when used together.
If you accidentally overdose on Axert, seek immediate medical advice or call the Poison Helpline at 1-800-222-1222.
Antidote: in cases of overdose, the stomach most be emptied as soon as possible by inducing vomiting, activated charcoal may also be used.
Axert should only be taken as needed, therefore the chances of missing a dose are rare. However two doses should not be taken within two hours of each other.