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Colchicine Price, 0.6 mg Tablets, and US Shipping
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What Colchicine Is and How It Works
Colchicine is an oral anti-inflammatory medication used most often for gout flares, gout prevention, and certain autoinflammatory conditions. Many people search for the best colchicine price when planning long-term therapy, especially for colchicine 0.6 mg tablet strengths. At YouDrugstore, a licensed Canadian pharmacy headquartered in Manitoba, you can order brand or generic colchicine tablets online at Canadian prices. We coordinate sourcing and shipment through vetted partner pharmacies, and prescriptions are reviewed by licensed pharmacists before dispensing.
Colchicine works inside white blood cells to reduce the inflammatory response to crystal deposits. In gout, it helps control pain and swelling triggered by urate crystals. It is also used in familial Mediterranean fever (FMF), and many clinicians use colchicine for pericarditis and recurrent pericarditis care. The most common dose form is the colchicine 0.6 mg tablet, taken by mouth once or twice daily depending on the indication.
We partner with licensed and vetted international pharmacies so you receive authentic brands and quality generics across a broad selection at affordable pricing.
Dosage and Usage
Follow your prescriber’s directions. Typical regimens include:
- Gout flare: 1.2 mg at first sign of pain, then 0.6 mg one hour later (total 1.8 mg on day 1). Continue 0.6 mg once or twice daily until the flare settles.
- Gout prevention: 0.6 mg once or twice daily. Dose may be lower in older adults or those with kidney issues.
- FMF: Often 1.2 mg to 2.4 mg daily in one or two doses. Titrate to control attacks while keeping side effects low.
- Pericarditis (off-label): Many use 0.5 to 0.6 mg once or twice daily for 3 months in acute episodes, or up to 6 months for recurrent cases, with adjustments for body weight and tolerability.
Missed dose guidance:
- If you miss a dose, take it when you remember unless it is close to the next dose. Do not double up.
Storage and travel:
- Store at 20 to 25 C (68 to 77 F) in a dry place away from light.
- Keep tablets in the original container with the label while traveling.
- Carry extra doses and avoid leaving medicine in a hot car.
Important interactions and adjustments:
- Avoid strong CYP3A4 or P-gp inhibitors (for example, clarithromycin, ketoconazole) with colchicine, especially if you have kidney or liver disease.
- Use caution with moderate inhibitors (verapamil, diltiazem) and medicines that raise myopathy risk such as some statins or cyclosporine.
- Lower doses are often needed in older adults and in chronic kidney disease (colchicine and CKD require careful monitoring).
Benefits and Savings
Colchicine lowers pain and swelling in acute gout when started early and reduces the risk of future flares when used for prevention. It can reduce attacks in FMF. Many clinicians include colchicine for pericarditis management to cut recurrence rates when used with an anti-inflammatory.
YouDrugstore offers Canadian pharmacy pricing on colchicine tablets and ships to the US. Ordering is simple online, and phone ordering is available where noted. Our customer-service chat is available during posted office hours if you need ordering help. Many customers see 60 to 80 percent savings compared to typical US prices, which is meaningful for long-term therapy.
You can select brand or generic when available, compare colchicine cost options, and choose the supply that fits your plan. Reorder reminders and multi-month supplies may help lower the monthly cost.
Side Effects and Safety
Common side effects:
- Diarrhea is the most frequent issue, especially at higher doses.
- Nausea, stomach pain, vomiting, and cramping may occur.
- Fatigue or headache sometimes appears early in therapy.
Serious risks are uncommon but require prompt medical care:
- Muscle pain, weakness, or dark urine (myopathy or rhabdomyolysis), especially with certain statins, cyclosporine, or strong CYP3A4 inhibitors.
- Low white blood cells or platelets, easy bruising, or infection signs.
- Numbness, tingling, or peripheral neuropathy symptoms with chronic use.
- Severe diarrhea, dehydration, or inability to keep fluids down.
Colchicine has a narrow safety margin. Do not exceed the prescribed dose. Avoid grapefruit products with colchicine. Discuss all medicines and supplements with your prescriber, including antibiotics and heart drugs. Seek urgent care after accidental overdose or if severe symptoms develop.
Onset Time
For acute gout, many people notice improved pain within 18 to 24 hours when therapy begins early in the flare. The response is better when started as soon as symptoms begin. For prevention in gout or FMF, benefits accrue over days to weeks as future attacks become less frequent. In pericarditis, symptom relief may begin within days, with extended use reducing recurrences.
Compare With Alternatives
NSAIDs such as Naproxen are a common option for acute gout or pericarditis when tolerated. NSAIDs can cause stomach irritation and may not suit people with certain heart, kidney, or bleeding risks.
Urate-lowering therapy treats the cause of gout. Allopurinol is used long term to reduce uric acid and prevent flares. It is often paired with colchicine during the first months of therapy to limit flares triggered by uric acid shifts.
Oral corticosteroids are another short-term option for acute gout or pericarditis when NSAIDs or colchicine are not ideal. Each approach has pros and cons based on other health conditions, drug interactions, and response to treatment.
Combination Therapy
For gout prevention, many use allopurinol and colchicine together during urate-lowering initiation. The colchicine gout medication helps suppress flares while uric acid levels are brought down. In pericarditis, clinicians often pair colchicine and ibuprofen to control pain and inflammation. The combination of ibuprofen colchicine should be individualized, and stomach protection may be needed in higher-risk patients.
Do not combine colchicine with strong CYP3A4 or P-gp inhibitors. Use caution with certain statins or fibrates because of muscle toxicity risk. Always keep your prescriber informed about every medicine you take.
Patient Suitability and Cost-Saving Tips
Colchicine is not right for everyone. People with severe kidney or liver disease may need lower doses or an alternative plan. Avoid combining colchicine and pericarditis therapies that raise interaction risk without medical guidance. Extra caution is needed for older adults and those with multiple medicines. Some patients use colchicine for pseudogout (CPPD) or for Behcets Disease, based on specialist advice. It can also be part of care plans for Familial Mediterranean Fever and Gout.
Ways to manage your colchicine cost:
- Choose generic colchicine tablets when available; they usually cost less.
- Compare package sizes and consider multi-month supplies to lower the per-month price.
- Set up simple reorder reminders so you do not run out during prevention therapy.
- Ask your prescriber about the lowest effective dose of colchicine medication for your situation.
To learn more about joint conditions, see our article Arthritis What Are The Most Common Forms Of Arthritis. This background can help when discussing colchicine and gout or colchicine and pseudogout with your care team.
Authoritative Sources
For detailed prescribing information, see the FDA Colchicine Prescribing Information, the Health Canada entry for Colchicine (DPD), and clinical guidance on pericarditis that often includes colchicine in pericarditis protocols.
You can order colchicine tablets from YouDrugstore at Canadian pharmacy pricing. We coordinate your order with partner pharmacies and provide prompt, express, cold-chain shipping to the US. If you need help with placing an order or checking availability, our customer-service team is ready during posted office hours.
Disclaimer: This page offers general information about colchicine drug uses, dosing, risks, and alternatives. It does not replace the advice of your own clinician. Always follow your prescriber’s instructions and local regulations on prescriptions and medicine use.
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What is colchicine used for?
Colchicine treats acute gout flares, helps prevent future gout attacks, and reduces attacks in familial Mediterranean fever. Many clinicians also use colchicine for pericarditis and recurrent pericarditis. The most common strength is colchicine 0.6 mg, taken once or twice daily depending on the indication and your prescriber’s plan.
How fast does colchicine work for a gout flare?
When started early in a flare, many people see pain begin to ease within 18 to 24 hours. The first-day regimen often uses 1.2 mg, then 0.6 mg one hour later. Continue 0.6 mg once or twice daily until symptoms settle. Take only as directed and avoid exceeding the dose.
What is the typical colchicine dose for prevention?
For gout prevention, colchicine 0.6 mg once or twice daily is common. The dose may be lower in older adults or with kidney or liver disease. For FMF, higher daily doses are sometimes needed. Your prescriber will adjust the regimen based on response, tolerability, and other medicines.
Are there important drug interactions with colchicine?
Yes. Avoid strong CYP3A4 or P-gp inhibitors such as clarithromycin or ketoconazole, especially if you have kidney or liver disease. Use caution with certain statins or cyclosporine due to muscle risks. Always review new prescriptions, over-the-counter products, and supplements with your care team before changes.
What side effects should I watch for?
Diarrhea, nausea, stomach pain, and vomiting are common and often dose related. Serious effects include muscle pain or weakness, dark urine, low blood counts, or signs of infection. Seek urgent care if these occur. Do not exceed your prescribed dose. Avoid grapefruit products which can raise drug levels.
How can I save on the colchicine price?
Choosing generic colchicine tablets often lowers cost. Comparing package sizes and ordering multi-month supplies can reduce the per-month price. Many customers save 60-80% versus typical US prices by ordering from a Canadian pharmacy. YouDrugstore also offers reminders so you can plan refills and avoid urgent purchases.
Can I take ibuprofen with colchicine?
Many clinicians combine colchicine and ibuprofen for acute pericarditis or for pain relief in gout when appropriate. This approach should be individualized based on your history, kidney function, bleeding risk, and other medicines. Ask your prescriber about the best plan and whether stomach protection is needed.