Tamoxifen is a prescription drug that has been in existence for a number of years. It’s the generic form whereas, Saltamox is the brand name. It can be prescribed to both men and women.
What is the Medicine Used for in Men?
To treat breast cancer
Males are at risk of breast cancer, although they do not have breast like females. They have a small quantity of breast tissue; breast of a man is identical to the breast of a young girl before she gets to puberty. In a girl, the tissue will grow and develop once puberty sets in, but in a man, it does not. There are different types of breast cancer, which affect men, though the cancers which affect the parts that produce as well as store milk are rare.
Males at risk of breast cancer are above 35 years; the chance of developing breast cancer increases with age. Males between 60 to 70 years are more prone to breast cancer. Below are risk factors for breast cancer:
Exposure of radiation on the chest
Breast enlargement termed as gynecomastia
Klinefelter’s syndrome – it’s a genetic condition, buts it’s rare
Cirrhosis – a severe liver disease
Ailments affecting the testicles like mumps orchitis or undescended testicles
If you detect a lump in the chest, it’s advisable to seek medical attention. Don’t ignore a lump since many males delay seeking medical help and do so when it’s already too late; when the symptoms are serious for example bleeding from the nipple. In such a point breast cancer may have advanced and spread. The health professional will perform a physical exam and you will undergo some tests like mammography and biopsies. The doctor may prescribe hormonal therapy such as Tamoxifen for men. Males with breast cancer respond well to hormonal therapy when compared to women. Why is this so? The majority of the men have breast cancer, which depends on hormones to grow and spread. A man’s body produces a minimal amount of estrogen and progesterone hormone. Some types of breast cancer cells have receptors for estrogen as well as progesterone hormones. If the hormones bind to these receptors, the growth of cancer cells is fueled. Tamoxifen works by stopping estrogen and progesterone from attaching on the breast cancer cells. Without estrogen and progesterone means the growth of cancer cells is hindered.
Other Uses for Tamoxifen
Males are also prone to prostate cancer; it’s believed to be among the most common cancers in men. Early diagnosis and treatment prevent complications; hence it’s advisable to go for annual checkups as well as screening since there aren’t early prostate cancer symptoms.
Androgen hormones are crucial for normal growth as well as the function of the prostate (a male reproductive gland which produces semen). Additionally, they are required by prostate cancer to grow and spread. Androgens mainly comprise of testosterone and dihydrotestosterone in males; they fuel the growth of cancerous and non-cancerous prostate cells. The hormones bind and activate the androgen receptor. Prostate cancer cells, which rely on androgens, are termed as androgen-dependent. Testicles mainly produce testosterone; however, a minimal amount of the hormone is produced by the adrenal glands located above the kidneys.
One of the treatments for prostate cancer is the hormonal therapy, which works as follows:
Minimize androgen production by the testicles
Inhibits actions of androgen in the body
Prevent release of androgens throughout the body
Androgen suppression therapy slows down the growth of cancer; the tumors shrink, although cancer may have spread to other body parts. The aim of the hormonal therapy is to manage cancer; the therapy places prostate cancer on hold for a handful of years and improves the symptoms such as bone pain and urinary issues. If hormonal therapy is used in males whose cancer has not spread or spread slightly, it kills cancer cells and shrinks the remaining gland. This makes it easier for the man to be treated later with surgery or radiotherapy.
Hormonal therapy is effective and has been beneficial to many men; nevertheless, many males will experience negative effects due to androgen suppression such as:
Breast enlargement in males is embarrassing and may lead to low self-esteem. Males may also have breast pain as a result of this condition. Thus men on androgen therapy are put on Tamoxifen for men to suppress breast enlargement and breast pain.
Also, the drug is used by bodybuilders to treat gyno. Bodybuilders use anabolic steroids, which lead to breast enlargement. It’s advisable to seek medical attention and the medical care provider may prescribe Tamoxifen. It works to treat breast enlargement by preventing the conversion of testosterone hormone into estrogen during a cycle, so the estrogen levels are decreased.
The drug is also used as a fertility pill in males with low sperm count. It increases sperm production by increasing testosterone levels. The tablet is taken orally and the dosage will depend on the condition being treated. But most of the times, the starting dose is 10 mg to 20 mg taken once daily. Adhere strictly on the dose prescribed, do not take more or less of the drug. To get the wanted effects, the dose may be adjusted.
Like any other drug, Tamoxifen for men lead to unwanted effects. Each man is different; hence the negative effects will vary from one man to another. Before you start taking the medicine, get to know from your physician on what to expect while on the medication; this will keep you prepared in case the side effects occur. If possible, ask the medical care provider to refer you to men who have been on the medicine. Learn from them on how the drug reacted to them and how they coped.
While on treatment, remember to be vigilant about the negative effects, consult the doctor on how to manage the negative effects. The side effects of the drug are similar to those experienced by women. Below are the undesired effects which you may encounter:
Memory and thinking problems
Many males find the side effects unbearable and stop taking the medication. It’s advisable to inform the medical practitioner if the undesirable effects become unbearable before you stop taking the drug; bear in mind the physician has put you on the drug because you will benefit more from it.
In 2015, the FDA approved flibanserin (Addyi), also known as “female Viagra,” for marketing after two previously failed attempts. Based on the theory that low libido in women, which is dubbed hypoactive sexual desire disorder (HSDD), is a result of an imbalance of neurotransmitters in the brain, flibanserin works by manipulating a variety of serotonin receptors, with some manipulated by excitation, while others are manipulated via inhibition. According to the prescribing information from Valeant Pharmaceuticals, the “mechanism of action in the treatment of premenopausal women with hypoactive sexual desire disorder is not known.”
How does flibanserin (Addyi) work?
Yes, this is true. But this is true for a lot of medications. Almost one in five medications lack a well-defined mechanism of action. However, flibanserin does not work anything like sildenafil (Viagra), (vardenafil) Levitra, and tadalafil (Cialis) do, which is by causing increased bl ...
This article primarily will center on GU infections of the bladder and kidney. But first, an introductory metaphor to illustrate the issue at hand.
Body Spaces and Stagnant Ponds
Look at any stagnant pond. Covered by green scum and stinky, it is an entirely different ecosystem from what is typical in a flowing, renewing, currents of water. The human body is no different. It doesn’t like standing collections of fluid. When that happens, the conditions become excellent for invaders who seize the opportunity to set up house.
Whether it’s fluid behind the ear drum of a child swimmer, bile stasis from gallstones interfering with drainage, or a consistent puddle of urine from incompletely emptying one’s bladder, one thing is certain: infection will occur. Our bodies are dynamic, and there are repetitive sequences (e.g., heartbeat), feedback loops (e.g., menstruation), and spaces awash with fluids that balance filling with emptying (e.g., the bladder). Anything in ...
Eliquis (generic apixaban) is an anticoagulant or blood thinner medication that delays the clotting of blood. It is approved by the US FDA in 2014 to treat deep vein thrombosis and pulmonary embolism and prevent their recurrence. It is also used to reduce the risk of blood clots and stroke in people who have atrial fibrillation.
What are blood thinners?
Blood thinners are prescription medications that prevent the formation of blood clots. It is also helpful in preventing existing clots from getting larger. Blood clots are dangerous; they usually form in the arteries, veins, and heart that can lead to blockages, heart attack, and stroke. There are two types of blood thinner medications: anticoagulant and antiplatelet. Eliquis belong to the anticoagulant type, specifically direct oral anticoagulant class, or DOAC.
Since mid-1950s, warfarin has been the mainstay of anticoagulant therapies. It belongs to the class of vitamin K antagonists (VKA) that blocks the circulatio ...