Inspra is a brand name of medication with the generic active ingredient called eplerenone, which is used to lower blood pressure in patients with hypertension. Inspra is also used to treat patients with heart failure.
Doctors prescribe Inspra alone or in combination with other medicines to treat mild and moderate hypertension. Inspra is also used to improve survival in patients with heart failure following a heart attack.
Inspra works by blocking the action of aldosterone, which is a hormone in the body involved in the development and progression of heart failure that can occur after a heart attack. By blocking the action of aldosterone, Inspra reduces the symptoms of heart failure and also reduces the risk of hospitalization and death from heart failure.
Your doctor will decide the appropriate dose for you depending on the potassium level in your body and your kidney condition. To treat heart failure, the usual starting dose is one 25mg tablet taken orally once daily. In about four weeks, your doctor may increase your dose to one 50mg tablet once daily. The maximum daily dose for heart failure is 50mg. To treat high blood pressure, the usual dose is 50mg taken orally once daily. The maximum daily dose for hypertension is 100mg.
These may not be all the side effects of Inspra 50mg.
You should not use this medication in combination with certain other drugs that affect the elimination of Inspra. Do not use Inspra if you have severe liver impairment, high levels of potassium in your blood or severe kidney impairment.
It is important to tell your doctor prior to using this medication if you have kidney disease, diabetes or liver disease. As well, tell your doctor about other medications you are using, such as lithium for mood disorders and potassium supplements or salt substitutes containing potassium.
Store at room temperature, safely away from the reach of children.
Heart failure is a serious condition where the pumping action of the heart cannot meet the body’s needs for blood and oxygen. The heart tries to make up for this in several ways. The heart chamber enlarges so it can contract more strongly and pump more blood. With an enlarged heart, your body starts to retain fluid, your lungs get congested with fluid and your heart begins to beat irregularly. The heart increases its muscle mass because the contracting cells of the heart get bigger. Also, the heart pumps faster to increase the output. Symptoms vary widely depending on the type of heart failure and may include shortness of breath, coughing/wheezing, swollen ankles, dizziness, rapid heart rate and need to urinate at night. Heart failure has many causes or underlying risk factors. The most common is damage to the heart muscle caused by a heart attack (myocardial infarction). The second most common cause is undiagnosed and untreated high blood pressure (hypertension). Your doctor may prescribe two or more medications to treat heart failure. In addition to these heart failure medications, other drugs may be used such as nitrates for chest pain, statins to lower cholesterol or blood-thinning medications to help prevent blood clots.
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