GENERIC - PRESCRIPTION REQUIRED!
Nortriptyline 10 mg
nortriptyline hydrochloride
Product:
Nortriptyline
Strength:
10 mg
Pack Size:
100 capsule(s)
Manufacturer:
Apotex
*Maximum: 90-day supply  Maximum 90-day supply
Please note:

Due to policy restrictions and health regulations, YouDrugstore.com can only dispense a maximum 90-day (3 month) supply of your medication based on a valid prescription. A valid prescription must be written and signed by a licensed physician and must have a prescription date that is no more than one year (365 days) old. All new prescriptions are verified with a signing physician.

If you place an order that exceeds a 90-day (3 month) supply of your medication, YouDrugstore will adjust your order to conform to policy restrictions. This adjustment will be confirmed with you before your order is processed.

Quantity
Price per pack
1 PACK+
$33.39 USD
2 PACKS+
$30.24 USD
3 PACKS+
$28.35 USD
4 PACKS+
$27.09 USD
5 PACKS+
$22.68 USD
6 PACKS+
USD$20.16 20.16USD

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General Information

Nortriptyline is the trade name of a prescription drug containing nortriptyline hydrochloride (commonly referred to as nortriptyline) as the active component. This medication belongs to a class of drugs called tricyclics antidepressants used in the treatment of depression. Common off-label uses include treatment of chronic pain, bed wetting in children, anxiety disorders, irritable bowel syndrome, migraine prophylaxis and in the treatment of attention deficit hyperactivity disorder (ADHD). Nortriptyline is manufactured by Apotex Corp. and is available as oral capsules in bottle size of 100 capsules.

Active Ingredient

Nortriptyline is a tricyclic antidepressant whose effects are thought to be due to the increase in serotonergic neurotransmission (chemicals in the brain), it also blocks the receptors responsible for sedation, anticholinergic effects and hypotensive. (Dry mouth, constipation, blurred vision and urinary retention).

Conditions Treated

 

Label use

  • Depression

Off-label use

  • Chronic pain
  • Bedwetting in children
  • Anxiety disorders
  • Irritable bowel syndrome
  • Migraine prophylaxis
  • Attention deficit hyperactivity disorder (ADHD)

Generic and brand names

Some brand medication containing notriptyline include Aventyl and Pamelor. There are a few generic brands for the oral tablets such as Nortriptyline, a generic that is very much effective as the originator.

Indications and Dosage Information

Note: Consult with your Doctor how to take this medication.

  • Adult dose is 25 mg three to four times a day normally started at a low dose and dose above 100 mg a day are not recommended. Used for depression.
  • The geriatric dose for depression is 30 to 50 mg daily in divided doses.

Side effects

Some of the side effects include:

  • Anticholinergic: some of the signs and symptoms include; blurred vision, dry mouth, urinary retention, constipation, paralytic ileus, delayed micturition, dilation of the urinary tract.
  • Cardiovascular: some of the signs and symptoms include; hypertension, palpitation, tachycardia, myocardial infarction, arrhythmias, stroke, hypotension heart block.
  • Psychiatric: some of the signs and symptoms include; state of confusion with hallucinations mostly in elders, insomnia, agitation, anxiety, disorientation, panic hypomania, nightmares, exacerbations of psychosis.
  • Allergic: some of the signs and symptoms include: drug fever, urticarial, skin rash, petechial, itching, edema, cross sensitivity with other tricyclics and photosensitivity.
  • Neurologic: tingling, seizures, numbness, paresthesia of extremities, ataxia, tremors, tinnitus.

Note: These may not be all the side effects of this medication. Consult with your Doctor.

Warnings and Precautions

Contraindications

Do NOT take:

  • If you are hypersensitive to nortriptyline.
  • This medication is contraindicated when used in acute recovery of myocardial infraction.
  • The concurrent use of other tricyclic antidepressants and nortriptyline with a MAO is fatal.

Precautions

  • Depressed patients may still be in danger of committing suicide after the initiation of treatment therefore the least possible dose should be initiated.
  • May elevate or lower the blood sugar levels of patients.
  • Dosage adjustments is a necessity when nortriptyline is used with other sympathomimetic and anticholinergic drugs.
  • Take with food to avoid irritation
  • Troublesome patients may be aroused with the use of nortriptyline therefore close monitoring is required.
  • The use of alcohol and nortriptyline may potentiate the effects of nortriptyline and lead to an increase danger of over dosage or increase risk of suicidal attempts.

Note: These may not be all the precautions and contraindications of this medication. Always consult with your Doctor.

Drug Interactions

Taking Nortriptyline with certain drugs can either potentiate their effects in the body or nullify them, it may affect the manner in which these drugs work or vice versa. Therefore you should know the medicines you take and always remember to tell your healthcare provider and pharmacist when you are prescribed new medicine. Below are some examples of medicines that may interact with this medication when used together.

 

  • Abiraterone
  • Acetophenazine
  • Alogliptin
  • Altretamine
  • Zolpidem
  • Zopiclone
  • Zotepine
  • Warfarin
  • Vandetanib
  • Venlafaxine
  • Triprolidine
  • Topiramate
  • Triazolam
  • Tranylcypromine
  • Sulfamethoxazole

 

Should also avoid consuming alcohol and excessive quantities of caffeine contained in coffee or tea.

Note: This list is not complete so always find out with your doctor if the current medication you taking can interfere with your medication.

 

Frequently Asked Questions About Nortriptyline

 

What is it?

Nortriptyline is an FDA approved drug for use in the treatment of depression.

How does it work?

This medication works by interfering with certain neurotransmitters (serotonin) in the brain thereby regulating their output.

How to store it

  • Store away from direct sunlight and heat.
  • Store at room temperature between 15˚C-30˚C.
  • Do not store in a humid place (bathroom).
  • Keep in a well closed container.
  • Keep out of the reach of children.

What medical conditions are treated with this drug?

  • Depression
  • Chronic pain
  • Bed wetting in children
  • Anxiety disorders
  • Irritable bowel syndrome
  • Migraine prophylaxis

Are there generic medications containing Nortriptyline?

Yes, there are a few generic brands for the oral tablets such as Nortriptyline manufactured by Apotex.

Is Nortriptyline called differently in Canada than the USA?

NO, nortriptyline is the active ingredient contained in this medication and it is not called by a different name in the United States. Although there are brand medications with the same active ingredient and those can differ. Aventyl and Pamelor are brand medications.

How and when to take it?

You should take Nortriptyline exactly as your healthcare provider instructs you to.

  • This medication should be taken with food.
  • Do not skip any doses or stop taking it abruptly, even if you begin to feel better, unless you develop severe side effects from its usage. Talk to your doctor.
  • The adult dose for depression is 25 mg three to four times a day normally started at a low dose and dose above 100 mg a day are not recommended.
  • The geriatric dose for depression is 30 to 50 mg daily in divided doses.

Note: your doctor might recommend a dose different from the above dose, do not try and change the directions issued by your doctor.

 

Why do doctors prescribe this medication?

 

For the treatment of:

  • Depression

Doctors tend to prescribe this medication off-label to treat:

  • Chronic pain
  • Bedwetting in children
  • Anxiety disorders
  • Irritable bowel syndrome
  • Migraine prophylaxis

What if I overdose on it?

If you accidentally overdose on Nortriptyline, seek immediate medical advice or call the Poison Helpline at 1-800-222-1222.

Symptoms of over dose include: Fever, hypothermia, agitation, vomiting, dry mouth, seizures, dilated pupils, ataxia, confusion, restlessness, hyperactive reflexes, respiratory depression dizziness, rapid heart rate, renal failure blurred vision etc.

Note: This list is not complete therefore you should ask your pharmacist or doctor about possible signs and symptoms of over dosage.

What if I miss a dose?

Take a dose as soon as you remember, however if you remember just an hour or two before the next dose, only take one dose. Never try to double up on the doses.

 


 

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