Buy Bonefos (Clodronate Disodium) 400 mg Online | Low Cost

Buy Bonefos (Clodronate Disodium) 400 mg Online

Whta is Bonefos (Clodronate Disodium)?

Bonefos is the brand name of a prescription drug containing clodronate as the active ingredient. Clodronate belongs to a group of medications called bisphosphonates. This medication is used to prevent the loss of calcium from the bones or high blood calcium levels, to maintain normal blood calcium levels, and to help manage bone diseases associated with cancer. Bonefos is manufactured and marketed by Rhone-Poulenc Rorer.

This medication is also known under the following names in the USA and Canada:

  • Brand names: Bonefos
  • Generic names: Clodronate Disodium

Active ingredients

The active ingredient in Bonefos is clodronate, which works by interfering with certain chemicals in the body to prevent the loss of calcium from the bones.

Conditions treated

Bonefos is used for the treatment and management of:

  • Calcium loss from bones;
  • Normal blood calcium levels;
  • Bone diseases associated with bone cancer.


Make sure to always take your medication exactly as instructed by the doctor. The dosage given by the doctor may differ from the ones indicated below. Please do not try and alter your dosage in order to change treatment outcome without consulting with the doctor. Your doctor takes into consideration several factors such as age, body weight, other medication and other medical conditions before determining the dosage specific for your case.

  • The capsules (Bonefos) should be swallowed whole with plain water.
  • The usual recommended dose varies based on different conditions and treatment goals. The dose generally ranges from 1,600mg to 3,200mg best taken on an empty stomach with a glass of water as a single dose or in divided doses.

Do not take Bonefos with milk because it decreases the amount of the medication absorbed from the body.

The doctor may prescribe doses that are different from the recommended doses above. You should not change your dose without consulting your doctor.

Bonefos side effects

Bonefos may exhibit some level of side effects. If the side effects are intolerable, see your doctor or pharmacist. Side effects include, but are not limited to:

  • Diarrhea;
  • Loss of appetite;
  • Nausea;
  • Stomach pain;

Talk to your doctor and seek immediate medical attention if any of the following occur:

  • Difficulty breathing, wheezing;
  • Mouth pain;
  • Muscle cramps in the hands, arms, feet, legs, or face;
  • Skin rash and hives;
  • Swelling;
  • Unusual tiredness or weakness.

This may not be a complete list of side effects.

Warnings and precautions

It is important to inform your doctor of any known allergies that you may have to medications, especially if you have reacted to any fungal medications before. Some medical conditions may affect or may be affected by this medication. Tell your doctor of any current of chronic conditions that you may have before you start using Bonefos.

  • Talk to your doctor before taking Bonefos capsules if you any form of kidney problems or impairments;
  • Talk to your doctor before taking Bonefos capsules if you suffer from or have had swelling, numbness of the jaw, pain, a heavy jaw feeling, or if you have lost teeth;
  • Tell your dentist that you are being treated with this medication before undergoing any dental procedures;
  • Talk to your doctor if you suffer from low calcium levels because clodronate may cause low calcium levels;

Please note the safe and effective use in children has not been established. As well, the safe and effective use of Bonefos during pregnancy and breastfeeding has not been established; therefore, use should only be made if the benefits outweigh the risk.

Talk to your doctor and/or pharmacist about other possible precautions and warnings.


  • The use of Bonefos is contraindicated in patients who are hypersensitive to clodronate or any of the excipients used in the formulation.

Drug interactions

The use of Bonefos may cause some interactions when used concurrently with certain medications. This sometimes may lead to bad effects in the body and affect the functionality of both medications.

  • Aminoglycosides (e.g., gentamicin, tobramycin)
  • Bisphosphonates
  • Calcitonin
  • Calcium-containing intravenous solutions (e.g., ringer's solution)
  • Corticosteroids (e.g., prednisone)
  • Dietary supplements containing calcium, iron, magnesium, or aluminum
  • Loop diuretics (e.g., furosemide)
  • Mithramycin
  • Diclofenac
  • Ibuprofen
  • Naproxen
  • Ketoprofen
  • Phosphate supplements

Inform your doctor of all medications being taken, including non-prescription supplements.


  • Store away from direct sunlight and heat.
  • Store at room temperature.
  • Do not store in a humid place (bathroom).
  • Keep out of the reach of children.