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Product Information

What is Sectral?

Sectral is the trade name of a prescription drug containing of acebutolol as the active component. Acebutolol belongs to a group of heart medications called beta-blockers and it is used in the treatment of mild-to-moderate hypertension and angina pectoris due to ischemic heart diseases, normally used in combination with other drug like water pills. It is manufactured by Sanofi-Aventis Pharmaceuticals, and is available in different strengths of 100mg, 200mg, and 400mg tablets.

Active ingredient

Acebutolol is the active components of Sectral, and it works to lower high blood pressure and also in angina (chest pain due to reduce oxygen in the heart) patients. Sectral works by stopping/blocking beta-receptors in cardiac muscles, leading to a reduction in blood pressure.

Conditions treated

• High blood pressure
• Angina pectoris due to ischemic heart disease (long term management)

Generic vs brand name

Acebutolol is the generic version of this medication. The generic medication is just as effective as the brand name drug.

Dosage information

Use your medication as directed by your healthcare professional. If you are not sure of how to, please check with your doctor. It is recommended to take your daily dose Sectral at the same time every day. The dose for each patient should be individualized and adjusted accordingly when used together with other anti-hypertensive drugs.

For high blood pressure (hypertension)

• The recommended dose is 100mg twice a day, if an adequate response is not obtained after a week, it can be increase to 200mg twice a day and further increments can be done every 2 weeks until the desired effects are acheived. The maintenance dose is 400mg to 800mg daily in 2 divided doses.

For angina pectoris

• The recommended initial dose is 200mg twice a day and can be increased to a maximum of 300mg twice a day if a satisfactory result is not obtained. The maintenance dose is usually between 200mg to 600mg daily in 2 divided doses.

The doctor may be required to prescribe doses that differ from the above dosages, do not change your dose or take the medication contrary to the doctor’s directions.

Side effects

Sectral may exhibit some side effects, which include, but are not limited to the list below. Report any new experience or feeling occurring after the use of Sectral.

• Tiredness
• Nausea
• Dizziness
• Skin rashes
• Lightheadedness

Contraindications

• The use of Sectral is contraindicated in patients who are hypersensitive to acebutolol, or any of the excipients used in the formulation.
• The use of acebutolol is contraindicated in patients with tumor of the adrenal gland.
• The use of acebutolol is contraindicated in patients with circulation problems, low blood pressure, heart problems, and heart rhythm disorder.

Precautions

Always remember to inform your doctor of any allergies or medical condition you may have, medications you are currently taking, if you are breastfeeding or pregnant, and any other important health conditions you might have.

Do not take Sectral without consulting a doctor if you:

• Are less than 18 years old;
• Are planning to become pregnant or are already pregnant;
• Are using any anti-cancer medications;
• Are diagnosed with a liver, kidney disease, and diabetes;
• Have had stroke or any heart attacks;
• Have psoriasis or hyperthyroidism;
• Have experienced any heart problems in the past or heart failure.
• Have chronic obstructive pulmonary disease, emphysema, asthma, and bronchitis.
• Have abnormal blood sugar levels or diabetes.

Drug interactions

Taking Sectral with certain drugs can either potentiate their effects in the body or nullify them. Therefore, you should know the medicines you take and always remember to tell your healthcare provider when you are prescribed new medicine.

• Other medications used to treat high blood pressure, such as calcium channel blockers
• Reserpine
• Noradrenaline
• Isoprenaline
• Ephedrine
• Phenylephrine
• Phenylpropanolamine
• Disopyramide
• Amiodarone
• Digoxin
• Fingolimod
• Albuterol
• Salmeterol
• Ibuprofen
• Naproxen, celecoxib
• Tricyclic antidepressants
• Barbiturates
• Phenothiazines
• Cyclopropane
• Trichloroethylene

Frequently asked questions

How to store Sectral?

• Store away from direct sunlight and heat.
• Store at room temperature.
• Do not store in a humid place.
• Keep in a closed container.
• Keep out of the reach of children.

What if I overdose on Sectral?

• If you accidentally overdose on Sectral, seek immediate medical advice or call the Poison Control Helpline at 1-800-222-1222. Symptoms of overdose include bradycardia, pulmonary edema, hypotension, bronchospasm and hypoglycemia, cardiogenic shock, congestive heart failure, AV block, depressed level of consciousness, conduction defects, and rarely, hyperkalemia

What if I miss a dose of Sectral?

Take a dose as soon as you remember; however, if you remember shortly before the next dose, only take one dose. Never double up on the doses.