APO-AZITHROMYCIN 250 MG is the trade name of a prescription drug containing Azithromycin as the active component. Azithromycin is a macrolide antibiotic that is used to treat a variety of infections that affect the body, ranging from inner ear, sinus, throat, respiratory tract, pelvis, skin, as well as some sexually transmitted infections. Our APO-AZITHROMYCIN is manufactured by Apotex Corp and is available as an oral tablet in a blister pack of 6 tablets. The tablets are oval, white, biconvex film coated tablets, engraved “AZ250” on one side and “APO” on the other side. Azithromycin was first approved by the FDA in November 1, 1991.
Azithromycin is absorbed into your bloodstream when it reaches your stomach. The drug works by attacking different parts of the bacterial cells. This prevents the bacteria from multiplying and growing, and kills the existing bacteria already present at the site of infection. By stopping the growth of the bacteria, and killing the existing bacteria, the symptoms of the infection should go away if treatment is successful
Unlike other macrolides, Azithromycin has a distinct long half-life and this enables a once daily dosing of the antibiotic. Depending on the intention of the healthcare professional and type of infection, the adult dose varies from 250-500mg once daily dosing. (See table 1)
Recommended Dose/Duration of Therapy
Acute bacterial exacerbations of chronic bronchitis (mild to moderate).
500 mg as a single dose on Day 1, followed by 250 mg once daily on Days 2 through 5 or 500 mg once daily for 3 days.
Community-acquired pneumonia (mild severity) Pharyngitis/tonsillitis.
500 mg as a single dose on Day 1, followed by 250 mg once daily on Days 2 through 5.
Acute bacterial sinusitis.
500 mg once daily for 3 days.
Genital ulcer disease (Non-gonococcal urethritis and cervicitis).
One single 1 gram dose.
Gonococcal urethritis and cervicitis.
One single 2 gram dose.
Infections of the urethra or cervix
Infected throat or tonsils
Acute worsening of chronic bronchitis
Genital ulcers in men
Infected throat or tonsils
Acute sinus infections
Some of the side effects of APO-AZITHROMYCIN include:
Note: Serious allergic reactions such as swelling of the tongue, face, lips, trouble swallowing or breathing, throat tightness, rapid heartbeat, hoarseness, faintness, swollen lymph nodes, new onset of fever and hives require immediate medical attention.
*This list is not inclusive. Please consult your pharmacist for other side effects.
Do NOT take APO-AZITHROMYCIN if you
Have a history of hepatic dysfunction or cholestatic jaundice that happened as a result of using this medication.
Have had a severe allergic reaction to certain antibiotics in the macrolides class (e.g. erythromycin) including azithromycin or ketolide.
Before using this drug be sure to inform your healthcare professional of any allergies or medical conditions you may have, whether you are breastfeeding or pregnant, medications that you are using at the moment and any other important health aspect that you may have. APO-Azithromycin may be known to cause the following.
Exacerbate muscle weakness in patients with myasthenia gravis.
Fatal (including serious) skin and allergic reactions: Discontinue the use of azithromycin if such reactions occur.
Some cases of liver toxicity have been reported (severe and fatal cases). If you noticed any signs and symptoms of hepatitis, discontinue use of this medication.
Diarrhea associated with Clostridium difficile (a bacteria that causes diarrhea)
Cases of torsade’s de pointes and Prolongation of QT interval have been reported with the use of Azithromycin 250mg therefore fatality risk should be considered in patients with certain cardiovascular disorders, patients with known history of QT prolongation or torsade’s de pointes and those with pro-arrhythmic conditions.
Taking APO-Azithromycin with certain drugs can either potentiate their effects in the body or nullify them, it may affect the manner in which these drugs work or vice versa. Therefore you should know the medicines you take and always remember to tell your healthcare provider and pharmacist when you are prescribed new medicine. Below are examples of medicines that may interact with this drug.
The serum concentration of Acebutolol, Acetaminophen, Acetyldigitoxin, and Agomelatine can be increased when it is combined with APO-Azithromycin.
Coagulation time maybe increase when used in conjunction with warfarin.
The metabolism of Acenocoumarol, Albendazole can be decreased when combined with this drug.
Amitriptyline, Amoxapine may increase the QTc-prolonging activities of Azithromycin.
The use of Nelfinavir and Azithromycin can potentiate adverse effects such as hearing impairment and liver enzyme abnormalities therefore close monitoring is warranted.
** This list is not all inclusive and you should ask your pharmacist or doctor if APO-Azithromycin 250mg interacts with any medication you are taking.
It is an FDA approved drug for the treatment of infections such as: Ear infections, Community-acquired pneumonia, infected throat or tonsils etc.
It works by interfering (stopping) the bacteria from multiplying (producing more bacteria) leading to the death of the bacteria and treatment of the infection.
Store Tablets at 59˚F to 86˚F (20˚C to 25˚C).
Safely throw away any medicine that is out of date or no longer needed. Keep out of the reach of children.
You can buy APO-Azithromycin 250mg from us with a valid prescription.
Yes, there are a few generic brands for the oral tablets, APO-Azithromycin is also a generic brand, and is very much effective as the originator.
You should take this medicine exactly as your healthcare provider instructs you to.
Take with or without food.
Always complete the course of treatment
Do not skip any doses or stop taking it, even if you begin to feel better. Unless you develop severe side effects from its usage.
To treat bacterial infections.
An Infection is the invasion of a person’s body by disease causing agents (either bacterial or viral). The multiplication of these agents, and the reaction of host to these disease causing agents and their toxins.
If you accidentally overdose on APO-Azithromycin 250mg, seek immediate medical advice or call the Poison Helpline at 1-800-222-1222.
Take a dose as soon as you remember, however if you remember just an hour or two before the next dose, only take one dose. Never try to double up on the doses.