Health And Wellness

Health And Wellness

Female Viagra: Safety and Effectiveness

Female Viagra: Safety and Effectiveness
In 2015, the FDA approved flibanserin (Addyi), also known as “female Viagra,” for marketing after two previously failed attempts. Based on the theory that low libido in women, which is dubbed hypoactive sexual desire disorder (HSDD), is a result of an imbalance of neurotransmitters in the brain, flibanserin works by manipulating a variety of serotonin receptors, with some manipulated by excitation, while others are manipulated via inhibition. According to the prescribing information from Valeant Pharmaceuticals, the “mechanism of action in the treatment of premenopausal women with hypoactive sexual desire disorder is not known.” How does flibanserin (Addyi) work? Yes, this is true. But this is true for a lot of medications. Almost one in five medications lack a well-defined mechanism of action. However, flibanserin does not work anything like sildenafil (Viagra), (vardenafil) Levitra, and tadalafil (Cialis) do, which is by causing increased bl ...

Drug Interactions—the Top Interactions That Should Be on Your Radar

Drug Interactions—the Top Interactions That Should Be on Your Radar
Most complications that occur because of drugs mixing badly will occur while a patient is in the hospital. This is just a matter of the environment because the hospital is where the sickest patients go. The sheer volume and assortment of drugs increase the risk of an adverse drug event (ADE). Patients in the hospital are likely to be exposed to the newest medications as their diagnosis progresses during their admissions. Even though there are drug-interaction monitors in electronic health record (EHR) programs and a dynamic pharmacy, the sheer number of medications and the rapid introduction of newer marketplace medications not yet in the database puts these patients at risk for suffering an ADE. What about outside of the hospital? In the hospital, there is only one chart, so all the medications will be listed together. In the out-patient setting in private practices and clinics, patients who go to different doctors will have their entire roster of medications spread out ...

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