Nortriptyline is a tricyclic antidepressant (TCA) approved by the US FDA for the treatment of depression, but your doctor may also prescribe it for persistent pain, such as peripheral neuropathy, fibromyalgia, and postherpetic neuralgia. It may take days or weeks for tricyclic drugs to take effect, so it is not recommended for acute pain.
Antidepressants are mainly used for treating major depressive disorder, anxiety, and other mood disorders. They are often categorized based on their mechanism of action; each group/class of antidepressant work in different ways:
Monoamine Oxidase Inhibitors (MAOI) – iproniazid, harmaline, moclobemide, selegiline;
Dopamine Reuptake Inhibitors (DRI)– bupropion, amineptine;
Serotonin-Norepinephrine Reuptake Inhibitors (SNRI) – duloxetine, nefazodone, venlafaxine;
Selective Serotonin Reuptake Inhibitors (SSRI) – alaproclate, citalopram, fluoxetine, paroxetine, sertraline;
Selective Serotonin Reuptake Enhancer (SSRE ...
Schizophrenia is a mental illness that is catastrophic in respect to its debilitating features. It has “positive” symptoms of hallucinations, delusions, and disorganized thinking; “negative” symptoms of withdrawal; cognitive symptoms of impaired memory, learning, understanding, and problem-solving; and emotional symptoms that include depression, anxiety, and suicidal tendencies.
What is the logic in treating schizophrenia?
Since it is a genetic disorder that involves variations in neurotransmitters, with the most important one being dopamine, medications that alter dopamine as well as glutamate, GABA, and acetylcholine are the cornerstone of therapy.
Messing with neurotransmitters is serious business, which means that medications that manipulate them offer great promise as well as serious side effects. Nevertheless, no one wants to go back to the days before 1950 when psychiatric facilities were nothing more than prisons. When Thorazine (chlorp ...