Health And Wellness
Nortriptyline is a prescription-only medication used to relieve the symptoms of depression. It is more effective in treating endogenous depression than other depressive states. Endogenous depression is a sub-class of major depressive disorder that occurs due to the presence of an internal factor (genetic and biological) instead of an external stressor (environment or social). Nortriptyline is an active metabolite of amitriptyline—a tricyclic antidepressant (TCA) of the dibenzocycloheptene type. This medication is also useful for smoking cessation and for treating various types of pain.
How it works
This TCA works by regulating the chemicals in the brain that may be unbalanced in people with mood disorders. The exact mechanism of action of nortriptyline is unknown. It is believed that nortriptyline blocks the reabsorption of the neurotransmitter norepinephrine and inhibits the activity of serotonin, histamine, and acetylcholine either by acting at the neuronal membrane ...
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