Inflammation hurts. But that is just to get your attention. Pain, be it from inflammation, trauma, or even emotionally, is a warning sign that you need to pay attention to something. It’s how we survive as a species. When you bang your thumb with a hammer, the pain you get is your body’s way of telling you, “Don’t do that, stupid! You wanna lose your thumb?”
Not all pain warnings are expressed as elegantly as that, however. In the case of inflammation, besides the obvious warnings of pain and tenderness, there is at work a secret mission to fight the culprit causing injury and to heal and repair the damage done.
While the tissue itself swings into repair mode, it is your circulation that provides the inflammatory response that is the initial part of any healing. Tissue damage, infection, and foreign bodies (like splinters or in-grown hairs) all send out a distress call that mobilizes the cells of your body—white blood c ...
A funny thing happened on the way to treating diabetes—a welcome side effect became evident: weight loss. The medication, liraglutide, was originally approved in 20101 for assisting in the management of Type 2 diabetes. This was due to something called the incretin effect, which is an increase in insulin when glucose rises—something that is natural in most people but is faulty in diabetics. (Insulin is the body’s way of taking sugar into the system for the creation of energy or energy storage.) The normal incretin effect is caused by the body’s GLP-1 (glucagon-like peptide), which is the mechanism by which it helps control blood sugar. Liraglutide, which mimics the actions of GLP-1 (GLP-1 agonist), does the same thing, helping in the control of diabets.
GLP-1’s multitasking abilities
GLP-1, however, also serves as the body’s “fed” signal,2 which comes in handy before tackling the second half of that roast beef su ...