Health And Wellness

Health And Wellness

What is the Difference between Viagra and Cialis?

What is the Difference between Viagra and Cialis?
Viagra and Cialis belong to the drug class phosphodiesterase type 5 (PDE5) inhibitor that works for treating erectile dysfunction (ED), or the inability to attain and maintain an erection, in men. The main difference of the two is how long they stay in your system. Cialis (tadalafil) has the longest duration among widely used ED drugs in the market; its effect is said to last up to 36 hours compared to four- to six-hour duration of Viagra (sildenafil). Because Cialis can remain in your system longer, you don’t have to limit your sexual activity within a short timeframe. However, it can be a downside if you are taking other medications that may interact with the drug. PDE5 inhibitors work by improving blood flow to the penis. Erection is attained when the chambers of the penis called corpora cavernosa are filled with blood. The spongy tissues inside these chambers allows the pooling of blood, which leads to an erection. A person with erectile dysfunction may have ce ...

Can Nortriptyline Get You High?

Can Nortriptyline Get You High?
Nortriptyline hydrochloride is a tricyclic antidepressant used to treat symptoms of major depression in adults. It is also being used off label for anxiety disorder, neuropathic pain, and nicotine addiction. It is contraindicated in pediatric and young adult patients due to risk of suicidal ideation. Aventyl and Pamelor are the common brand names of nortriptyline that is used to treat depressive symptoms. Both are supplied in a capsule (10mg, 25mg, 50mg, 75mg) and oral solution (5ml, 10ml) form. The availability of more recent generation of selective serotonin reuptake inhibitors (SSRI) causes a decline in prescribing tricyclic antidepressant, but with regard to endogenous depression or melancholic subtype, nortriptyline has higher success rates than SSRIs. How tricyclics work? This medication is a 2nd generation tricyclic antidepressant approved for the treatment of depression. The exact mechanism of action of tricyclic antidepressants is not yet fully understood. It is b ...

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