Dexilant® for GERD and Erosive Esophagitis Relief

What Dexilant® Is and How It Works

Dexilant® (dexlansoprazole) is a proton pump inhibitor used to treat gastroesophageal reflux disease (GERD) and to heal and maintain healing of erosive esophagitis. It reduces stomach acid by blocking the gastric H+/K+ ATPase. The dual delayed-release design releases medicine in two phases for sustained effect. Strengths include 30 mg and dexilant 60 mg delayed-release capsules.

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This acid reflux medication Dexilant offers flexible dosing without regard to meals. Many people start with dexlansoprazole 60 mg for short-term healing of erosive esophagitis, then continue with 30 mg for maintenance or for heartburn relief in GERD. Read more in Dexilant Dexlansoprazole Uses, and see our condition guide for Gastroesophageal Reflux Disease.

Dosage and Usage

• Typical adult dosing: 60 mg once daily for up to 8 weeks to heal erosive esophagitis; 30 mg once daily to maintain healing and for GERD-related heartburn, as directed by the prescriber.
• Take capsules whole with water. Dexilant may be taken without regard to food.
• For those who have trouble swallowing: open the capsule and sprinkle the granules on 1 tablespoon of applesauce. Swallow without chewing immediately.
• Do not crush or chew the delayed-release granules. Do not split doses.
• Missed dose: take as soon as remembered unless it is near the next dose. Skip the missed dose if close to the next. Do not double.
• Some medicines need stomach acid for absorption (for example, ketoconazole, atazanavir). Discuss timing or alternatives with a healthcare professional.
• Use the lowest effective dose for the shortest duration suited to the condition.

• Store at 20–25 °C (68–77 °F). Excursions 15–30 °C (59–86 °F) are usually acceptable.
• Keep capsules dry and in the original bottle with the desiccant.
• Protect from heat and excess humidity. Do not freeze.
• For travel, keep medicine in your carry-on, in original packaging, and away from direct sunlight.
• Keep out of reach of children and pets.

Benefits and Savings

Dexilant provides once-daily symptom control and healing of erosive esophagitis. The dual delayed-release system supports 24-hour acid suppression and can be taken without regard to meals, which helps busy schedules. Many patients appreciate the simple transition from dexlansoprazole 60mg DR capsules for healing to 30 mg for maintenance.

Ordering from a Canadian pharmacy can reduce dexilant cost versus typical US retail. Expect 60–80% savings on many brand and generic options. Compare dexlansoprazole cost to the dexilant brand to find the best fit. Multi-month supplies can lower the per-month dexilansoprazole generic price, and you can set gentle reorder reminders at checkout.

Looking for deals? See our dexilant coupon page for current promotions.

Patients often compare dexilant price to the cost of other PPIs. Generic drug for Dexilant options may be available as dexlansoprazole 30 mg and dexlansoprazole DR 60 mg, which can offer meaningful savings.

Side Effects and Safety

• Common effects: diarrhea, abdominal pain, nausea, vomiting, gas, headache, and upper respiratory symptoms.
• Less common: constipation, dry mouth, dizziness, or rash.
• Long-term use risks: low magnesium, vitamin B12 deficiency, fundic gland polyps, and bone fracture risk in certain patients.
• Gastrointestinal infections, including Clostridioides difficile-associated diarrhea, may occur.

Serious reactions are uncommon but can include severe allergic reactions, acute interstitial nephritis, cutaneous or systemic lupus erythematosus, and severe diarrhea suggestive of infection. Reduced stomach acidity can affect absorption of some drugs (for example, erlotinib) and may interact with warfarin monitoring. Liver impairment may require caution. Report unusual symptoms to a clinician.

Onset Time

Some heartburn relief can begin within 1–3 days of starting therapy. Maximum acid control typically appears after several days as steady state is reached. Healing of erosive esophagitis is usually assessed at 4–8 weeks. Maintenance therapy helps sustain healing and reduce relapse of symptoms over time.

Compare With Alternatives

Omeprazole is a widely used daily PPI for GERD. It offers broad availability and low cost. For many patients, Omeprazole controls routine heartburn well, though dual delayed-release is unique to Dexilant.

Rabeprazole is another effective PPI for symptom relief and healing of erosive disease. Consider branded options like Pariet® when a prescriber prefers a specific agent or when prior response guides the choice.

Esomeprazole is a common alternative for GERD and erosive esophagitis. Some patients who need stronger acid suppression use Esomeprazole, while others do well on the once-daily flexibility of Dexilant. The best option depends on clinical history and tolerability.

Combination Therapy

• Short-term use with antacids can help breakthrough heartburn. Separate administration from other oral drugs if needed for absorption.
• For nocturnal symptoms, some clinicians add an H2-receptor antagonist at bedtime on an as-needed basis.
• For NSAID-related ulcer risk, a PPI may be combined with gastroprotective strategies, as advised by a clinician.
• For Helicobacter pylori eradication, a PPI is combined with antibiotics per guideline-based regimens.

Patient Suitability and Cost-Saving Tips

Dexilant is used in adults for GERD and erosive esophagitis. It may also be suitable for adolescents when prescribed. It is contraindicated in individuals with known hypersensitivity to dexlansoprazole, lansoprazole, or any component of the formulation. Caution is advised in those with severe hepatic impairment, osteoporosis risk, low magnesium, or vitamin B12 deficiency. Discuss pregnancy or breastfeeding with a healthcare professional.

To manage dexlansoprazole price, consider generic dexlansoprazole when available. A 90-day supply can reduce the monthly cost versus single packs. Compare generic drug for Dexilant options with the branded capsule to match clinical goals and budget. Enable reorder reminders during checkout so refills arrive on time. Prompt, express shipping helps keep therapy on track.

Authoritative Sources

FDA Prescribing Information for Dexilant (dexlansoprazole)

Manufacturer Product Page: Dexilant by Takeda

Health Canada Drug Product Database: Dexlansoprazole

Order Dexilant® from Youdrugstore.com: add to cart, upload your prescription, and we ship with prompt, express shipping.

This content is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.