Buy Differin Gel 0.1% Online From Canada - Low Prices
Differin Gel 0.1%
Our best price: $113.02 USD per pack
*Maximum: 90-day supply  Maximum 90-day supply
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Due to policy restrictions and health regulations, can only dispense a maximum 90-day (3 month) supply of your medication based on a valid prescription. A valid prescription must be written and signed by a licensed physician and must have a prescription date that is no more than one year (365 days) old. All new prescriptions are verified with a signing physician.

If you place an order that exceeds a 90-day (3 month) supply of your medication, YouDrugstore will adjust your order to conform to policy restrictions. This adjustment will be confirmed with you before your order is processed.

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Product type:
Active Ingredient(s):
0,1 %
Pack Size:
60 g
Differin Gel
Country of Origin:

How to order

You just need to add your medication to your cart in this page, submit your mailing information and payment details. We will ship your order directly to your home for a cheap cost in shipping or even FREE. Learn how to get free shipping here.

You need to have a valid prescription to buy this medication. Uploading your prescription is easy and can always get help from our expert customer representatives by calling in. You can ask your doctor to fax us your prescription directly to speed up the process. Check out our contact information here.

Why Buy From Us

We,, are a legitimate pharmacy in Canada and authorized to sell medication online. That means you can get the same price our regular customers pay when they walk into our pharmacy in Canada. We are in good standing with regulatory agencies in Canada such as the Manitoba International Pharmacists Association (MIPA) and the Canadian International Pharmacy Association (CIPA). Learn more about our Certifications and Accreditations here.

Product Information

What is Differin XP?

Differin XP is the brand name of a topical gel that contains 0.3% adapalene as its active ingredient. Adapalene belongs to a class of drugs known as retinoids and has skin renewal properties like vitamin A. This medication is indicated for treatment of acne vulgaris, otherwise known as severe acne, on the face, chest, and back in adults and children older than 9 years of age. It helps to decrease the severity of acne and also helps to accelerate the healing process.

Active ingredients

The active ingredient in this medication is adapalene. Adapalene is thought to work by unblocking blocked oil glands in the skin. It also affects cell growth and has mild anti-inflammatory properties.

Conditions treated

  • Acne vulgaris

This medication may also be used for other conditions not mentioned above.

Dosage information

Always use your medication exactly as instructed by the doctor. The dosage given by the doctor may differ from the ones indicated here. Please do not try and alter your dosage in order to change treatment outcome without consulting with the doctor. There are many factors considered by the doctor when determining the dosage for your specific case such as the patient profile (age, body weight, other medication and other medical conditions), the size of the area being treated, the condition being treated, and response to treatment.

This gel is meant to be applied to the affected area as required, usually once daily at night or as otherwise directed by your doctor. Please follow your doctor’s instructions and if you are unsure, read your information leaflet.

Wash the area with a non-medicated cleanser and pat dry. Apply a small amount of the gel (pea sized) thinly and rub gently until completely absorbed. Make sure you clean and dry the skin before applying the cream. Wash your hands immediately after applying the gel.

During the first weeks of treatment, the acne may appear to be getting worse. This is only because the gel is working subcutaneously on the pimples. These effects should wear off eventually. If they persist, you should contact your doctor. It may take up to 4 to 8 weeks in some cases before the results become evident.

Do not use more than the recommended dose. In order to get the best results out of this treatment, the gel must be applied regularly.

Side effects

This medication may exhibit side effects. If the effects are adverse and cannot be handled or tolerated, you should immediately report to your doctor or pharmacist. Some of the side effects include, but are not limited to:

  • Dry skin;
  • Peeling of the skin at the site of application;
  • Skin scaling;
  • Skin irritation;
  • Reddening of the skin;
  • Inflammation at the site of application.

If any of the above persist after 2 to 4 weeks of use, you should stop using the gel and inform your doctor. The doctor may need to prescribe another medication or adjust the dose to suit you.

This is not a complete list of side effects that may occur after using this medication. Please report to your doctor immediately if you are not feeling well after using this medication.

Warnings and precautions

It is important to inform your doctor of any known allergies that you may have to medication, especially if you have reacted to any retinoids before. Some medical conditions may affect or may be affected by this medication. Tell your doctor of any current or chronic conditions that you may have before you start using Differin XP.

Differin XP may make your skin more sensitive to the sun. Avoid overexposure to the sun. Always apply sunscreen before any prolonged periods of exposure. Consult your doctor if you develop blisters.

Do not apply this medication to broken skin or areas that are injured, infected, sunburned, or irritated. Do not apply to the eye, inner lip, mouth, or nose. If the cream does come in contact with any of these parts, flush with water.

Avoid using waxing products, electrolysis, and other hair removal products while you are on this medication.


The use of this medication is contraindicated if you have any of the following conditions:

  • Hypersensitivity to adapalene or any other related products;
  • Hypersensitivity to other vitamin-A related product such as retinoids;
  • Eczema;
  • Seborrheic dermatitis.

Drug interactions

Using this medication together with certain drugs may change the effects of one or the other. It is important to notify your doctor of any medication that you currently are taking or intend to use concurrently with Differin XP gel. This includes medication obtained with or without a prescription.

  • Products that contain alpha hydroxyl acids
  • Sulfur containing drugs
  • Quinolone antibiotics e.g. ciprofloxacin
  • Hair perming agents
  • Products than contain glycolic acid
  • Other acne treatment drugs e.g. isotretinoin
  • Dapsone
  • Medicated soaps and cleansers
  • Cosmetics with a strong drying effect
  • Salicylic acid
  • Hydrochlorothiazide
  • Resorcinol

This is not a complete list of drugs or substances that may interact with adapalene. You should report any side effects or feelings of uneasiness that may result from using this medication together with another drug/substance.

The medication listed above may interact with adapalene to varying degrees. The doctor would use his discretion to do a risk/benefit analysis of using the drugs involved before making a decision. Some of the interactions require no medical attention and will wear off as soon as the drugs have left the system. However, you should seek medical assistance if you feel uncomfortable and cannot tolerate the effects of using the drugs together.

Frequently asked questions

How to store it

  • Keep out of the sight and reach of children.
  • Store away from direct sunlight and heat.
  • Store at room temperature.
  • Keep in a closed container.

Is there an alternative generic brand to Differin XP?

No, there are no generic alternatives for this medication

What if I overdose on Differin XP gel?

This medication may have serious side effects if ingested. Symptom of overdose may include fainting and difficulty breathing. The chances of an overdose of Differin XP when it is applied topically are low or unlikely. Seek immediate medical attention or call the Poison Helpline at 1-800-222-1222. Call even if there are no symptoms of overdose.

What if I miss a dose of Differin XP gel?

Apply the missed dose as soon as you remember. If the time is closer to when you need to apply the next one, skip the missed dose.