Cialis (tadalafil) belongs to the second generation of phosphodiesterase 5 (PDE5) inhibitors—a group of drugs that serves as a first-line treatment for erectile dysfunction in men (ED). Tadalafil is also approved for the treatment of prostate enlargement. Eli Lilly and Company is the sole manufacturer of Cialis, but its patent is about to expire in September 2018. Losing exclusivity to their wonder drug means another company can manufacture a generic Cialis, which in return will cause a definite slide in sales. Branded drugs lose up to 90% of their earnings when generic versions are released in the market.
The lifestyle drug Cialis, like Pfizer’s Viagra, is a PDE5 inhibitor, which naturally degrades cyclic guanosine monophosphate or cGMP. The erection-assisting property of PDE5 inhibitor drugs occurs within the spongy erectile tissue of the penis. The penis is maintained in a flaccid state until contraction of the cavernosal muscle and constriction of penile ar ...
While it may still be taboo to talk about erection problems, finding help has never been easier. However, not all erectile dysfunction (ED) treatments are equal. Pharmacologically, PDE5 (phosphodiesterase type 5) inhibitors still rule the market. Sildenafil (Viagra), tadalafil (Cialis), and vardenafil (Levitra) are the popular options. Though they all belong to the same drug class, they are not the same and should not be used interchangeably, unless there’s a go signal from your doctor.
Pfizer has achieved a game-changing feat worldwide for releasing Viagra. Some people call it the “vitamin V” but it is still not the super drug ED sufferers believed it to be. After all, you need to plan your sexual activity within 4 hours of taking it, leaving no room for spontaneity. When Cialis, aptly nicknamed The Weekend Pill, was introduced as having a half-life of 17.5 hours, it was granted FDA approval the next year.
What a longer half-life means
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