Betaseron (Interferon beta-1b) Online 0.3 mg

What is Betaseron (Interferon beta-1b)?

Betaseron is the trade name of a prescription drug containing interferon beta-1b as the active ingredient. It is used in the treatment of multiple sclerosis (MS) in patients who have experienced their first episode of clinical exacerbation and show signs that indicate they have multiple sclerosis. It slows the progression of multiple sclerosis; hence, reducing the frequency of clinical exacerbation. Interferon beta-1b belongs to a class of interferons called cytokines. It should be noted that Betaseron does not cure multiple sclerosis; however, it slows down its progression and reduces the frequency of relapsing. It is manufactured by Bayer pharmaceutics.

Active ingredients

Interferon beta-1b is the active component of Betaseron, a protein molecule containing anti-inflammatory effects. The actual mechanism on how it works is unknown, but it is believed to works by reducing the number of inflammatory cells that cross the blood brain barrier and stimulates secretion of nerve growth factor which promotes the growth nerve cells. 

Conditions treated

It is used in the management/prevention of relapsing of multiple sclerosis in patients who have experienced clinical exacerbation or have an MRI indicating the presence of multiple sclerosis.

Dosage

Do not share your medication with any other patients, take the medicines as directed by your doctor.

1.       Before administration of Betaseron, the patients should be provided with antipyretics and/or analgesics to better flu-like symptoms.
2.       The initial recommended dose is 0.25ml (0.0625mg) administered every alternate day subcutaneously, increased by 25% every 2 weeks to a targeted dose of about 0.25mg every alternate day.

The safety of Betaseron in children under the age of 18 years has not been established.

Betaseron side effects

Some side effects may include, but not limited to, the list below. Seek emergency attention if side effects become bothersome or severe:

• At the injection site or area (itching, skin irritation, bruising, swelling, bleeding and pain)
• Development of flu-like symptoms (fever, sweating, chills, tiredness and muscle aches)
• Low red blood cells
• Tightness in the chest
• Skin rash

This may not be all of the possible side effects. Review the product pamphlet and speak to your pharmacist or doctor if you have any questions or concerns.

Warnings and Precautions

Contraindications

1. The use of Betaseron is contraindicated in patients that are hypersensitive to interferon beta-1b or any of the inactive ingredients used in the formulation of Betaseron.
2. It is contraindicated in children less than 18 years of age.

This may not be all of the relevant contraindications. Discuss your medical history with your doctor to ensure this medication is suitable for you.

Precautions

Before using any new medications, inform your doctors and/or pharmacist about any other medical condition that you may have and if you are allergies you may have. Tell your doctor if you are pregnant, breastfeeding or if you intend to become pregnant.

1. Betaseron should be used with caution in patients with a history of liver problems.
2. This medication should not be used in patients who are hypersensitive to Albumin, interferon or any of the ingredients in the formulation.
3. Patients with a history of depression should be monitored closely as Betaseron may increase suicidal tendencies.
4. Patients with a history of pre-congestive heart failure should be monitored closely for worsening of their conditions.
5. The drug may reduce blood cell count therefore patients’ blood cell counts should be monitored.
6. Patients may develop flu-like symptoms.
7. This medication should be used with caution in patients with a history of seizures.
8. This drug should not be administered during pregnancy and safe use of Betaseron in children under the age of 18 years has not been established.

This may not be all of the relevant warnings.

Drug interactions

Certain medications when used together with Betaseron may affect the effects other medications in the body. Tell your doctor and/or pharmacist about any herbal, over the counter or prescription medication you might be using.

1. Aminophylline
2. Oxtriphylline
3. Theophylline
4. Zidovudine

Storage

1. Store away from direct sunlight and heat.
2. Keep out of the reach of children

What if I overdose?

Seek emergency help immediately or call the Poison Helpline at 1-800-222-1222 if you suspect that you might have overdosed.

What if I miss a dose?

Take a dose as soon as you remember missing a dose, but if it’s almost time for the next dose, do not double dose.