Health And Wellness

General Health

Viagra—Myths and Realities

Viagra Myths and Realities
Viagra (sildenafil) and other similar products (Levitra and Cialis) are in the class of drugs known as phosphodiesterase type-5 (PDE5) inhibitors. When sildenafil failed to qualify as a product in the antihypertensive market, penile erection, one of its side effects, was used as an opportunity to market it as something that was never before offered, for a condition never medicinally treated before. Suddenly, impotence became a dysfunction called erectile dysfunction and dysfunction meant a medical abnormality that warranted treatment. The biochemistry Nitric oxide (NO) widens blood vessels, thereby increasing circulation, and also inhibits the breakdown of a cyclic guanosine monophosphate (CGM), which controls nitric oxide’s role in vasodilation, by phosphodiesterase. By inhibiting the breakdown of the controlling CGM phosphate, the nitric oxide can continue to vasodilate.  Viagra, a PDE5 inhibitor, took the market by storm when it was first made available. Beca ...

Thyroid Drugs

Thyroid Drugs
Thyroid Drugs Abnormalities of the thyroid fall into two categories: Hypothyroidism—This refers to under-functioning of the thyroid. Hyperthyroidism—This refers to over-functioning of the thyroid. Some other definitions Goiter: This is the swelling of thyroid tissue and can occur because of hypothyroidism. Thyrotoxicity: This is symptomatic hyperthyroidism with hyperactive metabolism. Thyroxine is the thyroid hormone T4 and is made in the thyroid. Tri-iodothyronine is the thyroid hormone T3 and is made in the thyroid. Thyroid-stimulating hormone is also known as TSH and is made in the pituitary gland of the brain when stimulated by hypothalamic TRH. TRH is the thyrotropin-releasing hormone and is made in the hypothalamus of the brain. A tale of two hormones Tri-iodothyronine (T3) is the active hormone of the body that controls the rate of metabolism, growth, and body temperature. T3 is broken down from thyroxine (T4), another thyroid ...

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