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What is Nortriptyline 10mg Used For?

What is Nortriptyline 10mg Used For?
Nortriptyline 10 mg film-coated tablet is a prescription medication called tricyclic antidepressant (TCA) that is used to treat depression. There are two major types of TCA: the first-generation tertiary amine, which includes amitriptyline and imipramine; and the subsequent secondary amine where nortriptyline belongs. The usual starting dose for treating depression with nortriptyline is 25mg to be taken three to four times a day. It is available under the trade names Pamelor, Allegron, Nortrilen, and Aventyl. While nortriptyline is not a first-line treatment for depression, mainly due to the availability of newer selective serotonin reuptake inhibitors or SSRIs, it is still more beneficial for endogenous depression or major depression of melancholic subtype. Tricyclic antidepressants Nortriptyline is synthesized by demethylation (removal of a methyl group) of the first-generation TCA, amitriptyline. Nortriptyline is therefore considered as the active metabolite of amit ...

Can Nortriptyline Get You High?

Can Nortriptyline Get You High?
Nortriptyline hydrochloride is a tricyclic antidepressant used to treat symptoms of major depression in adults. It is also being used off label for anxiety disorder, neuropathic pain, and nicotine addiction. It is contraindicated in pediatric and young adult patients due to risk of suicidal ideation. Aventyl and Pamelor are the common brand names of nortriptyline that is used to treat depressive symptoms. Both are supplied in a capsule (10mg, 25mg, 50mg, 75mg) and oral solution (5ml, 10ml) form. The availability of more recent generation of selective serotonin reuptake inhibitors (SSRI) causes a decline in prescribing tricyclic antidepressant, but with regard to endogenous depression or melancholic subtype, nortriptyline has higher success rates than SSRIs. How tricyclics work? This medication is a 2nd generation tricyclic antidepressant approved for the treatment of depression. The exact mechanism of action of tricyclic antidepressants is not yet fully understood. It is b ...

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